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	Provedor de dados BJMBR (4) Arq. Bras. Med. Vet. Zootec. (1) Autor Antonio,E.L. (5) Tucci,P.J.F. (5) Saraiva,R.M. (3) Kanashiro,R.M. (2) Portes,L.A. (2) Bonilha,A.M.M. (1) Campos,O. (1) Dos Santos,L. (1) Flumignan,R.L.G. (1) Ishigai,M.M.S. (1) Kanashiro-Takeuchi,R.M. (1) Levy,R.F. (1) Mello,A.F.S. (1) Moisés,V.A. (1) Picollo,C. (1) Santos,L. dos (1) Serra,A.J. (1) Mais... Palavra-chave Heart failure (2) Hemodynamics (2) Myocardial infarction (2) Myocardial infarction size (2) Rats (2) Anesthesia (1) Bland-Altman test (1) Echocardiogram (1) Echocardiography (1) Echocardiography and triphenyltetrazolium comparison (1) Electrocardiogram (1) Hepatic congestion (1) Hypotension (1) Pulmonary congestion (1) ROC curve (1) Thermoregulation (1) Xylazine-ketamine (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Info:eu-repo/semantics/other (1) Ano 2012 (1) 2008 (1) 2007 (1) 2006 (1) 2005 (1) País Brazil (5) Idioma Inglês (5)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 5 Primeira ... 1 ... Última A routine electrocardiogram cannot be used to determine the size of myocardial infarction in the rat BJMBR Bonilha,A.M.M.; Saraiva,R.M.; Kanashiro,R.M.; Portes,L.A.; Antonio,E.L.; Tucci,P.J.F.. Nine lead electrocardiograms of non-infarcted (N = 61) and infarcted (N = 71) female Wistar rats (200-250 g) were analyzed in order to distinguish left ventricle myocardial infarction (MI) larger than 40% (LMI) from MI smaller than 40% (SMI). MI larger than 40% clearly caused a deviation of ÂQRS and ÂT from normal values of 270-360 degrees to 90-270 degrees. Infarcted rats showed Q wave in D1 larger than 1 mm with 94% sensitivity and 100% specificity. The sum of QRS positivity in V1, V2 and V6 lower than 10 mm identified MI with 82% sensitivity and 100% specificity. The data showed that MI can be easily and reliably diagnosed by electrocardiogram in the rat. However, contradicting what is frequently believed, when specificity and sensitivity were analyzed... Tipo: Info:eu-repo/semantics/article Palavras-chave: Myocardial infarction size; Rats; Electrocardiogram; Echocardiogram; ROC curve. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000400016 Determination of myocardial infarction size in rats by echocardiography and tetrazolium staining: correlation, agreements, and simplifications BJMBR Dos Santos,L.; Mello,A.F.S.; Antonio,E.L.; Tucci,P.J.F.. Triphenyltetrazolium chloride (TTC) staining and echocardiography (ECHO) are methods used to determine experimental myocardial infarction (MI) size, whose practical applicability should be expanded. Our objectives were to analyze the accuracy of ECHO in determining infarction size in rats during the first days following coronary occlusion and to test whether a simplified single measurement by TTC correctly indicates MI size, as determined by the average value for multiple slices. Infarction was induced in female Wistar rats by coronary artery occlusion and MI size analysis was performed after the acute (7th day) and chronic periods (after 4 weeks) by ECHO matched with TTC. ECHO and TTC showed similar values of MI size (% of left ventricle perimeter) in... Tipo: Info:eu-repo/semantics/other Palavras-chave: Myocardial infarction size; Echocardiography and triphenyltetrazolium comparison; Bland-Altman test. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000300004 Hemodynamic and thermoregulatory effects of xylazine-ketamine mixture persist even after the anesthetic stage in rats Arq. Bras. Med. Vet. Zootec. Picollo,C.; Serra,A.J.; Levy,R.F.; Antonio,E.L.; Santos,L. dos; Tucci,P.J.F.. The xylazine-ketamine mixture (KX) is an anesthetic approach commonly administered to assess cardiovascular function in rodents. This study aimed to examine if the cardiovascular and thermoregulatory effects of KX could persist after the anesthetic state ceased in rats. Male Wistar rats were anesthetized with K (50mg/kg) X (10mg/kg) through the intra-peritoneal route. Hemodynamic and thermoregulatory repercussions were evaluated in animals in awake state, during an anesthetic depth and after complete recovery of anesthetized state. KX was efficient to significantly induce deep anesthesia in all rats after 10min. A complete recovery of anesthetized state was observed only after 210min. Compared with preanesthetic state and control animals that received no... Tipo: Info:eu-repo/semantics/article Palavras-chave: Anesthesia; Hypotension; Xylazine-ketamine; Hemodynamics; Thermoregulation. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000400011 Incidence of heart failure in infarcted rats that die spontaneously BJMBR Flumignan,R.L.G.; Kanashiro,R.M.; Saraiva,R.M.; Portes,L.A.; Antonio,E.L.; Ishigai,M.M.S.; Tucci,P.J.F.. The present study reports for the first time the incidence of congestive heart failure (CHF) in previously infarcted rats that died spontaneously. Previously, pulmonary (PWC) and hepatic (HWC) water contents were determined in normal rats: 14 control animals were evaluated immediately after sacrifice, 8 placed in a refrigerator for 24 h, and 10 left at room temperature for 24 h. In the infarcted group, 9 rats died before (acute) and 28 died 48 h after (chronic) myocardial infarction. Thirteen chronic animals were submitted only to autopsy (N = 13), whereas PWC and HWC were also determined in the others (N = 15). Seven rats survived 48 h and died during anesthesia. Notably, PWC differed in normal rats: ambient (75.7 ± 1.3%) < control (77.5 ± 0.7%) <... Tipo: Info:eu-repo/semantics/article Palavras-chave: Heart failure; Myocardial infarction; Rats; Pulmonary congestion; Hepatic congestion. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006001000008 Rats with high left ventricular end-diastolic pressure can be identified by Doppler echocardiography one week after myocardial infarction BJMBR Saraiva,R.M.; Kanashiro-Takeuchi,R.M.; Antonio,E.L.; Campos,O.; Tucci,P.J.F.; Moisés,V.A.. The severity of left ventricular (LV) dysfunction in rats with myocardial infarction (MI) varies widely. Because homogeneity in baseline parameters is essential for experimental investigations, a study was conducted to establish whether Doppler echocardiography (DE) could accurately identify animals with high LV end-diastolic pressure as a marker of LV dysfunction soon after MI. Direct measurements of LV end-diastolic pressure were made and DE was performed simultaneously 1 week after surgically induced MI (N = 16) or sham-operation (N = 17) in female Wistar rats (200 to 250 g). The ratio of peak early (E) to late (A) diastolic LV filling velocities and the ratio of E velocity to peak early (Em) diastolic myocardial velocity were the best predictors of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Heart failure; Myocardial infarction; Echocardiography; Hemodynamics. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001100016 Registros recuperados: 5 Primeira ... 1 ... Última

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